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What Is the RNA World Hypothesis?

Stated Clearly
Explainers
YouTube
2 HN users recommended this explainer2 months2016–2021 score 2
Years with an HN recommendation, 2007–2026

HN recommends it as an engaging, brief overview of the RNA world idea.

Stated Clearly explains the RNA world hypothesis, which resolves the chicken-or-egg problem of genes versus enzymes by proposing that RNA once did both jobs. It outlines how evolution could begin with RNA chains alone.

“Stated Clearly has a great video about the RNA world hypothesis ( ) if anyone's looking for an engaging overview.” (HN, 2021)

2 recommendations · 1 citations · Explainers · intro

3 Hacker News comments

From the HN archive; up to 20 kept per video, favoring different commenters. Recommendations first.

@lawpoop Dec 2016 Recommends
on HN thread A New Physics Theory of Life (2014)
Read more
Evolution probably goes back before cells. The first living thing would have to be a self-replicating molecule that uses energy. Different forms of this self-replicating molecule would have different reproductive success. There is a not-unpopular theory that the original form of life on earth was an RNA molecule. RNA is a special molecule, because it can both act as a store of data, and as an enzyme for catalyzing reactions. According to this theory, specialized data storage in the form of DNA evolved later, along with specialized enzymes. Here's a brief overview of the theory that shows how evolution could happen with chains of RNA only: [this video] Jack Szostak at Harvard has a great series of videos explaining this theory, and also a number of experiments that he and his students have performed. [link]
Brief overview of how evolution could occur with RNA chains only.
@joshquin Dec 2021 Recommends
on HN thread The RNA World Hypothesis
Stated Clearly has a great video about the RNA world hypothesis ( [this video] ) if anyone's looking for an engaging overview.
Engaging overview of the RNA world hypothesis.

Citations, criticism and jokes

@JumpCrisscross Apr 2017 Cites it
on HN thread Mimicking an impact on Earth’s early atmosphere yields all 4 RNA bases
You may be looking for the RNA world hypothesis [1] [2]. In essence, random bits of RNA combine and replicate "in the wild". The bits that replicate better become more prevalent, et cetera, et cetera . This system needs no metabolic process per se . Heating and cooling and/or an oscillating chemical environment , e.g. from the day and night cycle or the tides or a belching vent, could provide the energy to power these cycles. [1] [link] [2] [this video]
Cited as source for the RNA world hypothesis.

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